Now this is a pleasant surprise. The new version of Reason has guitar and bass amp modelling by Softube. Softube made some brilliant (and eye-wateringly expensive) ampsims back in the noughties and it will be interesting to see how they work in Reason.
I quote “Get great guitar or bass tones with the new amp and speaker models from Softube. The two devices come with first class modeling of classic amplifiers and cabinets combined with a selection of great-sounding presets that will help you find the tone you are after.”
Interestingly, the feature list still has Line 6 guitar and bass amps listed. Worth a look I think.
The Propellerhead site can be found here.